Positions
Assistant
Professor
Ph.D.
Postdoc
Postdoc
2019 - present
2005 - 2010
2011 - 2014
2014 - 2019
2023
2019
2018
2013
2011
2004
Department of Chemistry
National Taiwan University
The Scripps Research Institute
Thesis advisor: M. Reza Ghadiri
Yale University (Schepartz Lab)
Rockefeller University (Brady Lab)
Education & Research Experience
Honors and Awards
全英語授課教學優良獎
國立台灣大學 化學系 新進教師傑出研究獎助金
Rockefeller University PDA Career Development Award
Yale University Postdoctoral Scholar Travel Fund
Camille & Henry Dreyfus Postdoctoral Fellowship
Dr. An-Tai Chen Distinguished Research Scholarship
Bio
Curriculum Vitae
I was born and raised in Taiwan. After receiving my B.S. in Chemistry from National Taiwan University, I moved across the Pacific Ocean for graduate studies at the Scripps Research Institute with Professor M. Reza Ghadiri, where I worked on developing new DNA sequencing technologies and demonstrated that DNA movement at the single molecule level can be spatially and temporally resolved as it threads through a-hemolysin (a protein nanopore). Upon receiving my Ph.D. degree, I moved to Yale University (2011) to work with Alanna Schepartz and built the first beta-peptide bundle that binds sugars/polyols. My next stop was Rockefeller University (2014), where I developed Syn-BNP (synthetic-bioinformatic natural product), a culture-independent pipeline for the discovery of bioactive small molecules.
In the summer of 2019, I joined my alma mater, the Department of Chemistry at National Taiwan University, as an assistant professor to start my independent research career. In light of the fact that microorganisms use natural products to communicate with each other and interact with the environment, I see the study of natural products as a way to understand the chemical language used by microorganisms, the most abundant form of life on earth. Currently, my research entails three aspects on natural products: discovery, chemical synthesis, and enzymes responsible for their production.
Courses I teach at NTU include Advanced Chemical Biology (graduate level), Natural Product Chemistry, and Bioorganic Chemistry, and Biochemistry.
In my leisure time, I enjoy playing golf and piano.
Teaching and Outreach
Teaching and outreach works have inspired much of my research.
Bioorganic Chemistry [Chem2037]
Recent Literature in Chemical Research (seminar course) [Chem4000]
Biochemistry [Chem5000]
Natural Product Chemistry [Chem5118]
Advanced Chemical Biology I (graduate) [Chem7037]
[科普短文]《天然物研究的前世今生》2021.04.29 | CASE Press | case.ntu.edu.tw/blog/?p=36446
[科普短評]《AI首度開發新抗生素之專家回應》2021.03.18 | 新興科技媒體中心 | smctw.tw/3560
Contact
If you would like to join our team, forge a collaboration, or just chat about crazy research ideas, feel free to contact me.
+886 2 3366 8654 (Office)
+886 2 3366 8653 (Lab)
Department of Chemistry, Rm A521
National Taiwan University
國立台灣大學
化學系暨研究所 積學館 A521